Description

2,2,2-Trifluoro-N,n-Diisopropylacetamide is a versatile fluorinated acetamide derivative characterized by its unique trifluoromethyl group. This compound is a valuable building block and intermediate in advanced organic synthesis, prized for its ability to introduce fluorine atoms and modulate the physicochemical properties of target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of fluorinated drug candidates, including potential antivirals, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for novel ligands in transition metal catalysis and organocatalysis, enabling new synthetic methodologies.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials where fluorine incorporation is desired for thermal stability, chemical resistance, or unique surface properties.
• Fluorine Chemistry Research: A fundamental reagent for studying fluorination reactions and the effects of fluorine substitution on molecular conformation and reactivity.

Basic Information

Product Name	2,2,2-Trifluoro-N,n-Diisopropylacetamide
CAS No.	567-64-6
Molecular Formula	C8H14F3NO
Molecular Weight	197.20 g/mol
Synonyms	N,N-Diisopropyl-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N,N-bis(1-methylethyl)acetamide; Trifluoroacetic Acid Diisopropylamide; TFAA Diisopropylamide; Acetamide, 2,2,2-trifluoro-N,N-bis(1-methylethyl)-; N,N-Diisopropyltrifluoroacetamide
EINECS	209-296-7

Quality Control

Our 2,2,2-Trifluoro-N,n-Diisopropylacetamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a chemical intermediate. We provide comprehensive Certificates of Analysis (COA) with key specifications upon request, supporting your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.