Description

(8S,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-6,7,8,9,11,12,14,15,16,17-Decahydrocyclopenta[A]Phenanthren-3-One is a high-purity steroidal ketone, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry and structural framework make it an essential building block for pharmaceutical research and development. This compound is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for the production of steroid-based APIs and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs) and hormones.
• Biochemical Research: Used as a reference standard and starting material in steroid metabolism studies and receptor binding assays.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for constructing complex natural products and specialty chemicals.
• Process Development: Employed in route scouting and optimization for the commercial-scale manufacturing of steroid derivatives.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and biological activities of steroidal compounds.

Basic Information

Item	Details
Product Name	(8S,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-6,7,8,9,11,12,14,15,16,17-Decahydrocyclopenta[A]Phenanthren-3-One
CAS No.	566-91-6
Molecular Formula	C27H44O
Molecular Weight	384.64 g/mol
Synonyms	3-Keto-5α-cholestane; 5α-Cholestan-3-one; Cholestan-3-one; Dihydrocholesterol-3-one; NSC 8798; Allocholestan-3-one; 5α-Cholestane-3-one; 3-Oxo-5α-cholestane
EINECS	209-294-7

Quality Control

Our (8S,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-6,7,8,9,11,12,14,15,16,17-Decahydrocyclopenta[A]Phenanthren-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	128°C - 132°C
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.