Description

1H,1H-Pentafluoropropyl p-Toluenesulfonate is a specialized fluorinated sulfonate ester, a key building block in advanced organic synthesis. This compound is valued for its role as a versatile reagent for introducing the pentafluoropropyl group, enabling the creation of molecules with enhanced properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for developing novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs) containing fluorinated alkyl chains, which can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a key starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, imparting valuable properties like oil/water repellency, chemical resistance, and low surface energy.
• Fluorinated Surfactant & Lubricant Development: Acts as a building block for creating high-performance fluorosurfactants and lubricants with superior thermal and chemical stability.
• Cross-Coupling Reactions: Functions as an electrophile in transition metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	1H,1H-Pentafluoropropyl p-Toluenesulfonate
CAS No.	565-42-4
Molecular Formula	C10H9F5O3S
Molecular Weight	304.24 g/mol
Synonyms	Pentafluoropropyl Tosylate; 2,2,3,3,3-Pentafluoropropyl 4-Methylbenzenesulfonate; 4-Methylbenzenesulfonic Acid 2,2,3,3,3-Pentafluoropropyl Ester; 1H,1H-Pentafluoropropyl Tosylate; p-Toluenesulfonic Acid Pentafluoropropyl Ester; 2,2,3,3,3-Pentafluoropropyl p-Toluenesulfonate; PFP-OTs; Pentafluoropropyl p-Toluenesulfonate
EINECS	Contact for details

Quality Control

Our 1H,1H-Pentafluoropropyl p-Toluenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.