Description

p-Nitrophenylacetonitrile is a versatile aromatic nitrile compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the dual reactivity of the nitrile and nitro groups, enabling its use in constructing complex molecular frameworks for pharmaceuticals and agrochemicals. This high-purity building block is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing benzylamine or phenylacetic acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the nitrophenyl moiety is required for biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing azo dyes and other complex colorants.
• Organic Synthesis Building Block: Employed in heterocyclic chemistry, such as the preparation of indoles, quinolines, and other N-containing heterocycles important in material science.
• Chemical Research & Development: A valuable reagent for method development, catalysis studies, and exploring new reaction pathways in academic and industrial R&D labs.
• Ligand and Chelator Precursor: Used to synthesize specialized ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	p-Nitrophenylacetonitrile
CAS No.	555-21-5
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	(4-Nitrophenyl)acetonitrile; 4-Nitrophenylacetonitrile; p-Nitrobenzyl cyanide; 2-(4-Nitrophenyl)acetonitrile; 4-Nitrobenzyl cyanide; (p-Nitrophenyl)acetonitrile; NSC 406908; USAF EK-3945
EINECS	209-094-5

Quality Control

Our p-Nitrophenylacetonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	115 - 118 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.