Description

Phenylacetylene is a versatile terminal alkyne building block essential for organic synthesis and advanced material development. Its high reactivity, particularly in Sonogashira coupling and cycloaddition reactions, makes it a critical intermediate for creating complex molecular architectures. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and novel drug candidates via cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science: Serves as a monomer or precursor for conductive polymers, liquid crystals, and advanced organic frameworks (MOFs/COFs).
• Chemical Research: Fundamental reagent in academic and industrial R&D for exploring new catalytic cycles and organic transformations.
• Ligand Synthesis: Precursor for creating specialized phosphine and N-heterocyclic carbene (NHC) ligands used in catalysis.
• Fine Chemical Production: Intermediate in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Phenylacetylene
CAS No.	536-74-3
Molecular Formula	C8H6
Molecular Weight	102.13 g/mol
Synonyms	Ethynylbenzene; Benzene, ethynyl-; Acetylene, phenyl-; 1-Ethynylbenzene; Phenylethyne; Phenyl acetylene; Ethinylbenzene; (Phenylethynyl)
EINECS	208-645-1

Quality Control

Our Phenylacetylene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to relevant industry standards and can support requirements for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.548 - 1.552
Density (20°C)	0.928 - 0.932 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.