Description

Ethionamide Sulfoxide is a key pharmaceutical intermediate and metabolite of the anti-tuberculosis drug Ethionamide. This compound is of significant importance for research and development in medicinal chemistry, particularly in the study of drug metabolism, mechanism of action, and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focusing on anti-infective therapies.

Application

• Pharmaceutical Intermediate: Critical for the synthesis and development of Ethionamide and related anti-tuberculosis agents.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and bioanalytical studies to quantify drug metabolism.
• Medicinal Chemistry Research: Serves as a building block or precursor in the design and synthesis of new chemical entities for antibacterial drug discovery.
• Biochemical Research: Employed in studies investigating the mechanism of action of Ethionamide and bacterial resistance pathways.
• Quality Control & Analytical Testing: Used in pharmaceutical quality control laboratories to develop and validate analytical methods for impurity profiling.

Basic Information

Product Name	Ethionamide Sulfoxide
CAS No.	536-28-7
Molecular Formula	C8H10N2OS
Molecular Weight	182.24 g/mol
Synonyms	2-Ethylisonicotinamide 4-Oxide; 2-Ethylpyridine-4-carboxamide 1-Oxide; Ethionamide S-Oxide; 4-Pyridinecarboxamide, 2-ethyl-, 1-oxide; Trecator-Sulfoxide; 2-Ethylisonicotinic acid amide 1-oxide; α-Ethyl-4-pyridinecarboxamide 1-oxide
EINECS	Contact for details

Quality Control

Our Ethionamide Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.