Description

(2S,5β)-3,3-Dimethyl-7-Oxo-6α-[(1-Oxooctyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2β-Carboxylic Acid Sodium Salt is a key sodium salt derivative of a penicillanic acid sulfone, valued for its role as a crucial intermediate in advanced pharmaceutical synthesis. This compound matters for its structural significance in the development of β-lactamase inhibitors, which are essential for combating antibiotic resistance. It is primarily needed by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development and production of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of β-lactamase inhibitors, such as sulbactam and related compounds.
• Antibiotic Research & Development: Used in medicinal chemistry for creating novel antibacterial agents to address resistant bacterial strains.
• Fine Chemical Synthesis: Serves as a specialized intermediate in multi-step organic syntheses for complex molecules.
• Biochemical Studies: Employed in research to study enzyme inhibition mechanisms and structure-activity relationships (SAR).
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(2S,5β)-3,3-Dimethyl-7-Oxo-6α-[(1-Oxooctyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2β-Carboxylic Acid Sodium Salt
CAS No.	525-88-2
Molecular Formula	C18H27N2NaO5S
Molecular Weight	406.48 g/mol
Synonyms	Sodium (2S,5R)-3,3-dimethyl-7-oxo-6-[(1-oxooctyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 6-(Octanoylamino)penicillanic acid S,S-dioxide sodium salt; CP-45,899-2 sodium salt; Sulbactam precursor sodium salt; Sodium 6β-(octanoyl-amino)penicillanate 1,1-dioxide; Betamaze intermediate; Sodium 6β-(octanoylamino)penicillanate sulfone
EINECS	Contact for details

Quality Control

Our (2S,5β)-3,3-Dimethyl-7-Oxo-6α-[(1-Oxooctyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2β-Carboxylic Acid Sodium Salt is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Microbial Limits	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.