Description

[6S,(+)]-6-[(1S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-2-Methylisoquinolin-1-Yl]Furo[3,4-E]-1,3-Benzodioxol-8(6H)-One is a high-purity, complex organic compound belonging to the tetrahydroisoquinoline alkaloid class. This compound is valued for its specific stereochemistry and serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Organic Synthesis Reagent: Used in complex multi-step syntheses to construct intricate molecular architectures due to its fused ring system and stereogenic centers.
• Biochemical Research: Serves as a reference standard or a probe in pharmacological studies to investigate receptor interactions and biological pathways.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Natural Product Analog Synthesis: Used to create analogs of naturally occurring isoquinoline alkaloids for structure-activity relationship (SAR) studies.

Basic Information

Product Name	[6S,(+)]-6-[(1S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-2-Methylisoquinolin-1-Yl]Furo[3,4-E]-1,3-Benzodioxol-8(6H)-One
CAS No.	524-46-9
Molecular Formula	C₂₃H₂₅NO₆
Molecular Weight	411.45 g/mol
Synonyms	(+)-Glaucine; (S)-Glaucine; D-Glaucine; NSC 336579; 1,2,9,10-Tetramethoxyaporphine; Glaucine; Furo[2,1-h][1,3]benzodioxolo[6,5,4-de]quinoline-6,7,9,10-tetrol, 5,6,6a,7-tetrahydro-1,2,10,11-tetramethoxy-6-methyl-, (6aS)-; 5,6,6a,7-Tetrahydro-1,2,10,11-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline-6,7,9,10-tetrol
EINECS	208-357-1

Quality Control

Our [6S,(+)]-6-[(1S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-2-Methylisoquinolin-1-Yl]Furo[3,4-E]-1,3-Benzodioxol-8(6H)-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets exacting research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) confirming identity, purity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.