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3β-[(3-o-Methyl-2,6-Dideoxy-L-Lyxo-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide CAS NO 507-88-0


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CAS No.:507-88-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(3-o-Methyl-2,6-Dideoxy-L-Lyxo-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. Its complex steroidal structure with a sugar moiety is essential for developing potent and selective therapeutic agents targeting cardiovascular functions. This compound is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel cardioprotective drugs and in-depth pharmacological studies.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel cardiac glycosides and related steroidal drugs.
  • Biochemical Research: Used as a reference standard and active probe in studies of sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac cell signaling pathways.
  • Preclinical Development: Employed in the discovery and optimization phases for new cardioprotective and inotropic agents.
  • Academic Research: Utilized in university and institutional labs for investigating the structure-activity relationships (SAR) of cardenolide derivatives.
  • Analytical Standard: Acts as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.

Basic Information

Item Detail
Product Name 3β-[(3-o-Methyl-2,6-Dideoxy-L-Lyxo-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No. 507-88-0
Molecular Formula C₃₀H₄₄O₉
Molecular Weight 548.67 g/mol
Synonyms Gitoxigenin 3-O-α-L-diginoside; 3β-[(3-O-Methyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)oxy]-11α,14-dihydroxy-19-oxo-5β-card-20(22)-enolide; Lanadoxin; α-Acetyldigoxin; 16-Acetylgitoxin; 3-O-α-L-Diginosylgitoxigenin; 3β-[(3-O-Methyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
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Quality Control

Every batch of 3β-[(3-o-Methyl-2,6-Dideoxy-L-Lyxo-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to support your regulatory and research needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time corresponds to reference standard
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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