Description

2-Trifluoromethyl-2-Propanol CAS NO 507-52-8 is a versatile fluorinated alcohol characterized by its unique trifluoromethyl group, which imparts significant chemical stability and lipophilicity. This compound is highly valued as a critical building block and intermediate in advanced organic synthesis, particularly for introducing fluorine-containing motifs. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors who require high-purity fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Acts as a precursor in the synthesis of fluorinated liquid crystals and dielectric fluids for display technologies and electronic applications.
• Polymer & Resin Modifier: Incorporated to create specialty fluoropolymers and coatings with improved chemical resistance, low surface energy, and thermal stability.
• Organic Synthesis Reagent: Employed as a fluorinating agent or protecting group in complex multi-step synthetic routes in academic and industrial R&D laboratories.
• Solvent & Reaction Medium: Utilized as a specialty solvent for specific reactions that benefit from its unique polarity and volatility profile.

Basic Information

Product Name	2-Trifluoromethyl-2-Propanol
CAS No.	507-52-8
Molecular Formula	C4H7F3O
Molecular Weight	128.09 g/mol
Synonyms	1,1,1-Trifluoro-2-methyl-2-propanol; 2-(Trifluoromethyl)propan-2-ol; Hexafluoro-tert-butanol; HFB; Perfluoro-tert-butanol; (Trifluoromethyl)dimethylcarbinol; α,α,α-Trifluoro-tert-butyl alcohol; 2-Methyl-2-(trifluoromethyl)propanol
EINECS	208-064-9

Quality Control

Our 2-Trifluoromethyl-2-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.320 - 1.330
Density (g/mL at 20°C)	1.250 - 1.270

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.