Description

Fluoroacetonitrile CAS NO 503-20-8 is a versatile and highly reactive organic nitrile building block, distinguished by the presence of a fluorine atom. This unique structure makes it a critical intermediate for synthesizing complex fluorinated molecules, offering enhanced metabolic stability and lipophilicity in final products. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where the introduction of fluorine is a key design strategy.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where fluorine improves efficacy and environmental persistence.
• Fluorinated Material Precursor: Serves as a monomer or intermediate in the creation of specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Reagent: Employed in cycloaddition reactions and as a cyano source for constructing heterocycles and complex organic frameworks in R&D.
• Radiotracer Development: Utilized in the synthesis of fluorine-18 labeled compounds for Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	Fluoroacetonitrile
CAS No.	503-20-8
Molecular Formula	C2H2FN
Molecular Weight	59.04 g/mol
Synonyms	Fluoroacetonitrile; Monofluoroacetonitrile; 2-Fluoroacetonitrile; Acetonitrile, fluoro-; Fluoromethyl cyanide; UN 3273; EINECS 207-967-3
EINECS	207-967-3

Quality Control

Our Fluoroacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flames. Due to its highly volatile nature, containers must be kept tightly sealed and under appropriate conditions (recommended 2-8°C or as specified) to prevent evaporation and maintain product integrity. Keep away from strong oxidizers, acids, and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.