Description

Penilloic Acid is a key organic intermediate and degradation product of penicillin antibiotics. This compound is of significant importance in pharmaceutical research and development, particularly in the study of β-lactam antibiotic stability, metabolism, and impurity profiling. It serves as a critical reference standard and building block for analytical chemists, process development scientists, and researchers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of penilloic acid impurities in penicillin-based drug substances and products.
• Antibiotic Degradation Studies: Essential for research into the stability, breakdown pathways, and shelf-life of β-lactam antibiotics.
• Metabolite Research: Employed in pharmacokinetic and metabolic studies to understand the fate of penicillin derivatives in biological systems.
• Process Chemistry: Acts as an intermediate or starting material in the synthesis of novel β-lactam structures or for analytical method development.
• Quality Control Laboratories: Critical for developing and validating HPLC, LC-MS, or other analytical methods to ensure drug purity and safety.
• Academic Research: Used in universities and research institutes for studies related to antibiotic resistance, enzymology (e.g., β-lactamase activity), and medicinal chemistry.

Basic Information

Product Name	Penilloic Acid
CAS No.	501-34-8
Molecular Formula	C8H12N2O4S
Molecular Weight	232.26 g/mol
Synonyms	D-α-Benzylpenilloic Acid; (2R)-2-Amino-2-(1-carboxy-3-methylbutyl)aminoacetic Acid; Benzylpenilloic Acid; Penicilloyl Amine; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, (2S,5R,6R)-; Degradation product of Penicillin G; Benzylpenicilloic Acid
EINECS	207-922-5

Quality Control

Our Penilloic Acid is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of specific impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.