Description

3-Fluorophenylacetonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its value lies in providing a reactive cyano group and a fluorine-substituted phenyl ring, enabling precise molecular construction for high-value intermediates. This compound is critically needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries seeking to introduce fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Material Research: Used in the creation of fluorinated components for electronic display materials and organic light-emitting diodes.
• Fluorinated Fine Chemical Production: Serves as a starting material for synthesizing various fluorinated benzylamines, acids, and heterocycles.
• Cross-Coupling Reactions: Suitable for palladium-catalyzed reactions like Suzuki or cyanation reactions to form complex biaryl structures.
• Academic & Contract Research: Valuable reagent for methodological development and exploring new fluorination chemistry in academic and industrial labs.

Basic Information

Product Name	3-Fluorophenylacetonitrile
CAS No.	501-00-8
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	(3-Fluorophenyl)acetonitrile; 3-Fluorobenzyl cyanide; m-Fluorophenylacetonitrile; 2-(3-Fluorophenyl)acetonitrile; 3-Fluorobenzeneacetonitrile; α-Cyano-3-fluorotoluene; 3-Fluoro-α-tolunitrile
EINECS	207-906-6

Quality Control

Every batch of 3-Fluorophenylacetonitrile is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic processes. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is available for each shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.