Description

Phenylephrine is a potent and selective α-1 adrenergic receptor agonist, widely recognized for its vasoconstrictive properties. This compound is a critical active pharmaceutical ingredient (API) essential for ensuring product efficacy and safety in a range of medical and consumer health formulations. It is primarily utilized by pharmaceutical manufacturers, compounding pharmacies, and producers of over-the-counter (OTC) healthcare products.

Application

• Pharmaceutical Formulations: As a key API in nasal decongestant sprays, eye drops for mydriasis, and injectable solutions for hypotension management.
• Over-the-Counter (OTC) Medications: A primary ingredient in oral and topical decongestants for relief from cold, allergy, and sinus symptoms.
• Ophthalmic Solutions: Used to induce pupil dilation (mydriasis) for diagnostic eye examinations and surgical procedures.
• Veterinary Medicine: Employed as a vasopressor in veterinary practice for managing hypotension in animals.
• Compounding Pharmacies: Sourced for the preparation of customized medication strengths and formulations not available commercially.
• Research & Development: Serves as a standard reference compound in pharmacological studies of adrenergic receptors and cardiovascular research.

Basic Information

Product Name	Phenylephrine
CAS No.	59-42-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(R)-(-)-Phenylephrine; L-Phenylephrine; (-)-Phenylephrine; Metasympatol; Neo-Synephrine®; m-Synephrine; (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol; Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (R)-
EINECS	200-424-2

Quality Control

Our Phenylephrine is manufactured under strict quality management systems. We offer grades compliant with major pharmacopoeial standards, including USP and EP. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-50.0° to -53.0° (c=2 in water)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.