Description

Cephalothin Sodium CAS NO 58-71-9 is a first-generation, semi-synthetic cephalosporin antibiotic in its sodium salt form. It is a critical pharmaceutical active ingredient valued for its broad-spectrum bactericidal activity against a wide range of Gram-positive and some Gram-negative bacteria. This compound is essential for manufacturers in the pharmaceutical industry, particularly for the formulation of sterile injectable antibiotic products used in clinical settings to treat serious infections.

Application

• Primary Active Pharmaceutical Ingredient (API) for the manufacture of sterile injectable antibiotic formulations.
• Used in clinical and hospital settings for the treatment of severe infections caused by susceptible organisms, including respiratory tract, skin and soft tissue, and urinary tract infections.
• Key component in the production of generic pharmaceutical drugs under various brand names globally.
• Essential material for pharmaceutical research and development of new antibiotic formulations and combination therapies.
• Used in microbiological laboratories as a reference standard for antibiotic susceptibility testing and quality control.
• Critical for compounding pharmacies requiring specific antibiotic preparations for patient-specific treatment plans.

Basic Information

Product Name	Cephalothin Sodium
CAS No.	58-71-9
Molecular Formula	C16H15N2NaO6S2
Molecular Weight	418.42 g/mol
Synonyms	Cephalothin Sodium Salt; Sodium Cephalothin; (6R,7R)-3-[(Acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; 7-(2-Thienylacetamido)cephalosporanic Acid Sodium Salt; Cefalotin Sodium; Keflin Sodium; Cephalothinum Natricum; Cephapirin Impurity A (Cephalothin)
EINECS	200-403-7

Quality Control

Our Cephalothin Sodium is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to confirm compliance with relevant pharmacopeial monographs such as USP and EP. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to Standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	4.5 - 7.0
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Sterility (for sterile grade)	Sterile
Bacterial Endotoxins	< 0.20 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.