Description

Promazine CAS NO 58-40-2 is a phenothiazine derivative belonging to the class of typical antipsychotic agents. This compound is a critical intermediate in pharmaceutical synthesis, valued for its structural role in developing neuroleptic medications. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of psychotropic drugs and related chemical reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of antipsychotic and neuroleptic active pharmaceutical ingredients (APIs).
• Research & Development: Used in biochemical and pharmacological research to study dopamine receptor antagonism and neurological pathways.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis for the preparation of more complex phenothiazine derivatives with potential therapeutic activity.

Basic Information

Product Name	Promazine
CAS No.	58-40-2
Molecular Formula	C17H20N2S
Molecular Weight	284.42 g/mol
Synonyms	10H-Phenothiazine-10-propanamine, N,N-dimethyl-; N,N-Dimethyl-3-(phenothiazin-10-yl)propan-1-amine; Sparine; Protactyl; Talofen; Prazine; Dimethylaminopropylphenothiazine; 10-[3-(Dimethylamino)propyl]phenothiazine
EINECS	200-386-2

Quality Control

Our Promazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical intermediates and research chemicals. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.