Description

Perphenazine is a high-purity phenothiazine derivative belonging to the class of typical antipsychotic agents. This compound is critical for its potent dopamine receptor antagonism, which underpins its primary therapeutic value. It is an essential active pharmaceutical ingredient (API) for manufacturers in the global pharmaceutical industry, particularly for the formulation of antipsychotic and antiemetic medications. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final drug products.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of antipsychotic medications.
• Formulation of injectable and oral dosage forms for the management of schizophrenia and other psychotic disorders.
• Utilized in antiemetic preparations to control severe nausea and vomiting.
• Used in clinical research and reference standard development for pharmacological studies.
• Intermediate in the synthesis of more complex pharmaceutical compounds.
• Application in veterinary medicine for specific behavioral conditions in animals.

Basic Information

Product Name	Perphenazine
CAS No.	58-39-9
Molecular Formula	C21H26ClN3OS
Molecular Weight	403.97 g/mol
Synonyms	2,4,6-Trichloro-1,3,5-triazine; Trichlorotriazine; Cyanuric Chloride; sym-Triazine Trichloride; 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, trichloro-; TCT; Cyanuryl Chloride; 1,3,5-Trichloro-s-triazine
EINECS	200-392-0

Quality Control

Our Perphenazine is manufactured under strict quality management systems to meet the rigorous standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with relevant pharmacopeial guidelines (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.