Description

4-Nitroquinoline n-Oxide is a heterocyclic organic compound of significant interest in biochemical and pharmaceutical research. This compound matters as a potent research chemical, primarily utilized as a model mutagen and carcinogen in genetic toxicology studies. It is needed by research institutions, pharmaceutical R&D departments, and chemical manufacturers focused on developing and testing compounds for oncology research and safety assessment.

Application

• Genetic Toxicology Research: Widely employed as a standard positive control mutagen in bacterial reverse mutation assays (Ames test) and mammalian cell genotoxicity studies.
• Oncology Research: Serves as a model carcinogen to study tumor initiation, promotion, and the mechanisms of chemical carcinogenesis in laboratory settings.
• Biochemical Studies: Used to investigate DNA damage, adduct formation, and cellular repair pathways in molecular biology.
• Pharmaceutical Development: Acts as a tool compound for screening and validating potential chemopreventive or anti-carcinogenic agents.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research in mutagenesis and cancer biology.
• Chemical Synthesis Intermediate: Can serve as a specialized precursor or building block for synthesizing more complex quinoline derivatives for research purposes.

Basic Information

Product Name	4-Nitroquinoline n-Oxide
CAS No.	56-57-5
Molecular Formula	C₉H₆N₂O₃
Molecular Weight	190.16 g/mol
Synonyms	4-Nitroquinoline 1-Oxide; 4-NQO; 4-Nitroquinoline N-Oxide; 1-Hydroxy-4-nitroquinoline; NSC 17605; Quinoline, 4-nitro-, 1-oxide; 4-Nitroquinoline oxide
EINECS	200-276-4

Quality Control

Our 4-Nitroquinoline n-Oxide is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to yellow-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	152 - 156 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.