Description

3-Iodo-4-Azidophenethylamido-7-o-Succinyldeacetylforskolin is a highly specialized, multi-functional chemical probe derived from the forskolin scaffold, designed for advanced biochemical research and pharmaceutical development. This compound matters for its unique ability to act as a photoaffinity labeling agent and a crosslinker, enabling the study of protein-protein interactions and target identification in complex biological systems. It is primarily needed by researchers in academic institutions, pharmaceutical R&D laboratories, and biotechnology companies focused on signal transduction pathways, particularly those involving adenylate cyclase.

Application

• Photoaffinity Labeling: Used to covalently tag and identify biological targets, such as enzymes and receptors, upon UV light activation.
• Chemical Biology Probes: Serves as a critical tool for mapping protein interaction networks and studying cellular signaling mechanisms.
• Adenylate Cyclase Research: Acts as a derivatized forskolin analog for investigating the modulation and localization of adenylate cyclase activity.
• Proteomics Studies: Employed in activity-based protein profiling (ABPP) to discover novel drug targets and understand disease biology.
• Bioconjugation & Crosslinking: Utilized for creating stable conjugates between biomolecules due to its reactive azido and succinyl groups.
• Drug Discovery Platforms: Integral to high-throughput screening assays and the development of targeted therapeutic agents.

Basic Information

Product Name	3-Iodo-4-Azidophenethylamido-7-o-Succinyldeacetylforskolin
CAS No.	111399-48-5
Molecular Formula	C31H33IN5O7
Molecular Weight	714.53 g/mol
Synonyms	7-Deacetyl-7-O-succinyl-3-iodo-4-azidophenethylamidoforskolin; 3-Iodo-4-azidophenethylamido-7-O-succinyldeacetylforskolin; IAPSForskolin; Iodo-Azido-Phenethylamido-Succinyl-Forskolin; Forskolin Iodoazide Probe; 7-O-Succinyl-3-iodo-4-azidophenethylamido-7-deacetylforskolin; AC Probe Derivative; Photoactivatable Forskolin Analog
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-4-Azidophenethylamido-7-o-Succinyldeacetylforskolin is synthesized and purified under controlled conditions to ensure the highest standard of chemical purity and functional integrity. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when possible to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.