Description

Promazine Hydrochloride is a phenothiazine derivative pharmaceutical compound widely recognized for its neuroleptic properties. This active pharmaceutical ingredient (API) is critical for ensuring the quality and efficacy of finished pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of antipsychotic medications. Our supply is characterized by high purity and strict adherence to pharmacopeial standards, ensuring reliability for critical applications.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the formulation of antipsychotic and neuroleptic medications.
• Key component in the manufacture of generic pharmaceutical products for the treatment of schizophrenia and other psychotic disorders.
• Utilized in pharmaceutical research and development for studying phenothiazine derivatives and their mechanisms of action.
• Reference standard in analytical laboratories for quality control and method validation using HPLC, GC, or spectroscopy.
• Intermediate in the synthesis of more complex pharmaceutical compounds within the phenothiazine class.
• Used in preclinical and clinical studies to evaluate neurological effects and therapeutic profiles.

Basic Information

Product Name	Promazine Hydrochloride
CAS No.	53-60-1
Molecular Formula	C17H21N2S • HCl
Molecular Weight	320.88 g/mol
Synonyms	Promazine HCl; N,N-Dimethyl-10H-phenothiazine-10-propanamine Hydrochloride; 10-[3-(Dimethylamino)propyl]phenothiazine Hydrochloride; Prazine Hydrochloride; Sparine Hydrochloride; Protactyl; Talofen; Liranol; Calmotal; Sedistan
EINECS	200-185-8

Quality Control

Our Promazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmacopeial specifications, including identification, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with relevant standards. We support audits and can supply documentation for regulatory submissions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.