Description

Chlorpromazine is a prototypical phenothiazine antipsychotic agent, widely recognized for its significant role in modern psychopharmacology. Its primary value lies in its potent dopamine receptor antagonism, which provides a foundational therapeutic effect for managing psychotic disorders. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry, particularly for the production of antipsychotic and antiemetic medications. Global demand is driven by its critical use in both human and veterinary medicine for the treatment of schizophrenia, nausea, and agitation.

Application

• Pharmaceutical API: Primary use as the active ingredient in antipsychotic medications for treating schizophrenia and other psychotic disorders.
• Antiemetic Formulations: Used in drugs to prevent and treat severe nausea and vomiting, particularly in postoperative and cancer therapy settings.
• Sedative and Pre-anesthetic Agent: Employed for its calming and potentiating effects in surgical and intensive care preparations.
• Veterinary Medicine: Applied in animal health for managing behavioral disorders and as a tranquilizer.
• Research & Development: Serves as a critical reference standard and biochemical tool in neuroscience and pharmacological research.
• Intermediate for Derivatives: Acts as a chemical precursor for the synthesis of other phenothiazine-based pharmaceutical compounds.

Basic Information

Product Name	Chlorpromazine
CAS No.	50-53-3
Molecular Formula	C17H19ClN2S
Molecular Weight	318.86 g/mol
Synonyms	2-Chloro-10-(3-dimethylaminopropyl)phenothiazine; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine; CPZ; Thorazine; Largactil; Aminazine; Propaphenin; Chlorpromazinum; Hibanil; Megaphen
EINECS	200-045-8

Quality Control

Our Chlorpromazine is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, in compliance with major pharmacopoeial standards such as USP, EP, and BP. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.