Description

3-Fluoro-4-Bromoobenzyl Cyanide is a high-purity fluorinated and brominated aromatic nitrile building block. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic and display materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Functional Material Research: Employed in the synthesis of ligands for catalysis and monomers for specialty polymers.
• Chemical Biology Probes: Utilized as a versatile handle for creating fluorescent tags and molecular probes for biochemical assays.

Basic Information

Product Name	3-Fluoro-4-Bromoobenzyl Cyanide
CAS No.	499983-13-0
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	(3-Fluoro-4-bromophenyl)acetonitrile; 4-Bromo-3-fluorobenzyl cyanide; 2-(4-Bromo-3-fluorophenyl)acetonitrile; α-Cyano-3-fluoro-4-bromotoluene; (4-Bromo-3-fluorophenyl)acetonitrile; 3-Fluoro-4-bromobenzeneacetonitrile; NSC 83616
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Bromoobenzyl Cyanide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.