Description

Benzene, 1-Ethenyl-3-Fluoro-2-Methoxy- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a vinyl group, a fluorine atom, and a methoxy substituent on a benzene ring, enabling precise molecular modifications. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Acts as a fluorinated core unit for constructing advanced organic electronic materials with tailored electro-optical properties.
• Polymer Modification: Employed to introduce functional aromatic side-chains into polymers, altering thermal stability, solubility, and surface characteristics.
• Cross-Coupling Reactions: The vinyl group makes it a valuable substrate in Heck, Suzuki, and other palladium-catalyzed cross-coupling reactions for carbon-carbon bond formation.
• Fluorine Chemistry Research: A valuable model compound for studying the electronic effects of fluorine substitution adjacent to alkoxy groups on an aromatic system.

Basic Information

Product Name	Benzene, 1-Ethenyl-3-Fluoro-2-Methoxy- (9Ci)
CAS No.	499235-07-3
Molecular Formula	C9H9FO
Molecular Weight	152.16 g/mol
Synonyms	3-Fluoro-2-methoxystyrene; 1-Ethenyl-3-fluoro-2-methoxybenzene; 2-Methoxy-6-vinylfluorobenzene; 2-Fluoro-6-methoxystyrene; (3-Fluoro-2-methoxyphenyl)ethene; Vinyl-3-fluoro-2-methoxybenzene; 6-Fluoro-2-methoxystyrene; 499235-07-3
EINECS	Contact for details

Quality Control

Our Benzene, 1-Ethenyl-3-Fluoro-2-Methoxy- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.