Description

(R)-(-)-α-[(S)-2-(Diphenylphosphino)Ferrocenyl]Benzylamine is a high-value, chiral ferrocenylphosphine ligand, a cornerstone in asymmetric catalysis. Its significance lies in its ability to induce high enantioselectivity in a wide range of transition metal-catalyzed reactions, enabling the production of single-enantiomer intermediates crucial for advanced materials and pharmaceuticals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-purity chiral auxiliaries for complex synthetic routes.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, critical for synthesizing chiral amino acids, alcohols, and amines.
• Asymmetric C-C Bond Formation: Employed in cross-coupling reactions (e.g., Suzuki-Miyaura, Heck) and allylic substitution to construct complex molecular architectures with precise stereocontrol.
• Pharmaceutical Intermediate Synthesis: Key catalyst component for producing enantiomerically pure active pharmaceutical ingredients (APIs) and advanced drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and pesticides where biological activity is stereospecific.
• Fine Chemical and Fragrance Production: Facilitates the creation of high-value chiral flavor and fragrance compounds.
• Academic and Industrial R&D: A vital tool for methodological development in asymmetric synthesis and catalysis research.

Basic Information

Item	Details
Product Name	(R)-(-)-α-[(S)-2-(Diphenylphosphino)Ferrocenyl]Benzylamine
CAS No.	498580-48-6
Molecular Formula	C29H26FeNP
Molecular Weight	475.35 g/mol
Synonyms	(R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine; (R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine; (R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine; (R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine; (R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine; (R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine; (R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine; (R)-(-)-α-[(S)-2-(Diphenylphosphino)ferrocenyl]benzylamine
EINECS	Contact for details

Quality Control

Our (R)-(-)-α-[(S)-2-(Diphenylphosphino)Ferrocenyl]Benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding catalytic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light may degrade performance. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.