Description

4-Piperidinamine, 1-(Trifluoroacetyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its trifluoroacetyl-protected piperidine amine structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where it serves as a key building block to introduce specific pharmacological properties. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its structural motif for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in scale-up and pilot plant syntheses for the manufacture of target molecules under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	4-Piperidinamine, 1-(Trifluoroacetyl)- (9Ci)
CAS No.	497177-66-9
Molecular Formula	C7H11F3N2O
Molecular Weight	196.17 g/mol
Synonyms	1-(Trifluoroacetyl)-4-piperidinamine; 1-(Trifluoroacetyl)piperidin-4-amine; 4-Amino-1-(trifluoroacetyl)piperidine; N-(Trifluoroacetyl)-4-aminopiperidine; 4-Piperidinamine, N-(trifluoroacetyl)-; 1-Trifluoroacetyl-4-aminopiperidine; 4-Aminopiperidine-1-carboxylic acid trifluoroacetic anhydride adduct; TFAP
EINECS	Contact for details

Quality Control

Our production of 4-Piperidinamine, 1-(Trifluoroacetyl)- adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development under quality guidelines appropriate for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.