Description

Ethanone, 2-Cyclopentylidene-2-Fluoro-1-Phenyl- (9Ci) is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopentylidene moiety and a fluorine atom adjacent to the carbonyl, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to introduce fluorinated motifs, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key fluorinated synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing sterically defined, fluorinated ketone functionalities.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorine atom enhances compound stability and bioactivity.
• Material Science Research: Acts as a monomer or precursor for developing specialty polymers and advanced organic materials with tailored electronic or surface properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Organic Methodology Development: A valuable substrate for developing new fluorination reactions, carbonyl chemistry, and cycloaddition protocols in academic and industrial R&D settings.

Basic Information

Product Name	Ethanone, 2-Cyclopentylidene-2-Fluoro-1-Phenyl- (9Ci)
CAS No.	495418-36-5
Molecular Formula	C₁₃H₁₃FO
Molecular Weight	204.24 g/mol
Synonyms	2-Cyclopentylidene-2-fluoro-1-phenylethanone; 2-Fluoro-2-cyclopentylidene-1-phenylethanone; 1-Phenyl-2-cyclopentylidene-2-fluoroethanone; α-Fluoro-α-cyclopentylidenephenyl methyl ketone; 2-Fluoro-1-phenyl-2-cyclopentylideneethanone; (2-Cyclopentylidene-2-fluoro-1-phenylethanone)
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of Ethanone, 2-Cyclopentylidene-2-Fluoro-1-Phenyl- (9Ci) is analyzed using advanced techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.