Description

(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(4-Methoxy-3,5-Dimethylphenyl)Phosphino]Ferrocene is a highly sophisticated, chiral ferrocenyl diphosphine ligand designed for asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity in critical carbon-carbon bond-forming reactions, enabling the production of single-enantiomer intermediates. Pharmaceutical R&D laboratories and fine chemical manufacturers need this ligand for developing novel active pharmaceutical ingredients (APIs) and other high-value chiral molecules where optical purity is paramount.

Application

• As a premier chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective C-C cross-coupling and addition reactions.
• Critical for the research and development of novel therapeutic agents in medicinal chemistry.
• Production of single-enantiomer flavors, fragrances, and agrochemicals.
• Use in academic and industrial research to study and develop new asymmetric catalytic processes.
• Manufacture of advanced materials requiring precise chiral control.

Basic Information

Item	Details
Product Name	(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(4-Methoxy-3,5-Dimethylphenyl)Phosphino]Ferrocene
CAS No.	494227-37-1
Molecular Formula	C72H84FeN2O4P2
Molecular Weight	1151.24 g/mol
Synonyms	(S,S)-Alphar-Ferrocene; (S,S)-AlPhar-FerroPHOS; (S,S)-Alphar-FerroPHOS; (S,S)-1,1'-Bis[α-(Dimethylamino)benzyl]-2,2'-bis[bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocene; (S,S)-Alphar-Ferrocenyl Diphosphine Ligand; Alphar-FerroPHOS Ligand; Josiphos-type ligand derivative; Chiral ferrocenylphosphine ligand
EINECS	Contact for details

Quality Control

Every batch of our chiral ligands is produced and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identity confirmation via techniques like HPLC, NMR, and elemental analysis. Our commitment ensures the reproducible high performance required for sensitive catalytic applications in pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.