Description

(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-,2'-Bis[Bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino]Ferrocene is a highly sophisticated, chiral ferrocenyl diphosphine ligand designed for asymmetric catalysis. This compound matters because it provides exceptional enantioselectivity and catalytic activity in a range of transition-metal-catalyzed reactions, enabling the production of high-value, optically pure intermediates. It is primarily needed by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• As a premier chiral ligand for asymmetric hydrogenation reactions.
• Catalyst component in the synthesis of enantiomerically pure pharmaceutical intermediates and agrochemicals.
• Used in asymmetric C-C bond-forming reactions, such as cross-couplings and allylic substitutions.
• Critical for academic and industrial R&D in methodology development for new catalytic processes.
• Employed in the production of specialty chemicals requiring high optical purity.

Basic Information

Product Name	(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-,2'-Bis[Bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino]Ferrocene
CAS No.	494227-36-0
Molecular Formula	C66H48F24FeN2P2
Molecular Weight	1444.79 g/mol
Synonyms	(S,S)-Alphar-Ferrocene; Josiphos SL-J505-1; (S,S)-1,1'-Bis[α-(Dimethylamino)benzyl]-2,2'-bis[bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocene; (S,S)-Alphar-Ferrocene Ligand; (S,S)-Alphar-Ferrocenyl Diphosphine; (S,S)-Alphar-Fc; (S,S)-Alphar-Ferrocene SL-J505-1; (S,S)-Alphar-Ferrocene Josiphos Ligand
EINECS	Contact for details

Quality Control

Our high-purity chiral ligands are manufactured under strict quality protocols to ensure batch-to-batch consistency and performance. Each lot undergoes comprehensive analysis, including chiral HPLC, 31P NMR, and 1H NMR, to verify identity, enantiomeric excess, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 99.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.