Description

Carbamic Acid, [[4-(Hydroxymethyl)-4-Piperidinyl]Methyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, protected piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical agents and fine chemicals, offering a reactive scaffold for further functionalization. It is primarily sought by research institutions and industrial R&D departments engaged in medicinal chemistry, particularly for the synthesis of complex molecules targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable piperidine core.
• Peptidomimetic Synthesis: Employed in the construction of peptide analogs and mimetics where the piperidine structure imparts specific conformational or binding properties.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	Carbamic Acid, [[4-(Hydroxymethyl)-4-Piperidinyl]Methyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	493026-47-4
Molecular Formula	C13H26N2O3
Molecular Weight	258.36 g/mol
Synonyms	tert-Butyl N-[[4-(hydroxymethyl)piperidin-4-yl]methyl]carbamate; 4-[[(tert-Butoxycarbonyl)amino]methyl]-4-piperidinemethanol; 4-(Aminomethyl)-4-piperidinemethanol, N-BOC derivative; N-Boc-4-(aminomethyl)-4-piperidinemethanol; 1,1-Dimethylethyl N-[[4-(hydroxymethyl)-4-piperidinyl]methyl]carbamate; BOC-Pip(4-CH2OH)-CH2NH2; (4-((tert-Butoxycarbonylamino)methyl)piperidin-4-yl)methanol
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [[4-(Hydroxymethyl)-4-Piperidinyl]Methyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.