Description

Ethyl 4-(2,6-Difluorophenyl)-4-oxobutyrate is a high-purity organic ester building block characterized by its difluorophenyl and oxobutyrate functional groups. This compound is of significant commercial interest as a key synthetic intermediate in the production of advanced pharmaceutical and agrochemical active ingredients. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides and fungicides, leveraging the bioactivity of the difluorophenyl moiety.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials requiring fluorinated aromatic components.
• Chemical R&D: Employed in academic and industrial laboratories for method development and exploring new reaction pathways in organic synthesis.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethyl 4-(2,6-Difluorophenyl)-4-oxobutyrate
CAS No.	493004-53-8
Molecular Formula	C₁₂H₁₂F₂O₃
Molecular Weight	242.22 g/mol
Synonyms	4-(2,6-Difluorobenzoyl)butyric Acid Ethyl Ester; Ethyl 4-(2,6-Difluorobenzoyl)butyrate; 2,6-Difluorophenyl 4-Oxobutanoate Ethyl Ester; Butanoic acid, 4-(2,6-difluorobenzoyl)-, ethyl ester; Ethyl 4-Oxo-4-(2,6-difluorophenyl)butanoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2,6-Difluorophenyl)-4-oxobutyrate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.