Description

Ethyl (1R,2S)-2-Cyanocyclopropane-1-Carboxylate is a high-purity, chiral cyclopropane derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical research and development teams, agrochemical innovators, and specialty chemical manufacturers for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antiviral, anticancer, and central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the cyclopropane ring confers specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	Ethyl (1R,2S)-2-Cyanocyclopropane-1-Carboxylate
CAS No.	492468-16-3
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	(1R,2S)-Ethyl 2-Cyanocyclopropanecarboxylate; Ethyl (1R,2S)-2-Cyanocyclopropanecarboxylate; (1R,2S)-2-Cyano-cyclopropanecarboxylic Acid Ethyl Ester; trans-(1R,2S)-Ethyl 2-Cyanocyclopropane-1-carboxylate; (1R,2S)-Cyclopropanecarbonitrile, 2-carboxy-, ethyl ester; Chiral Ethyl Cyanocyclopropanecarboxylate; (1R,2S)-CCE
EINECS	Contact for details

Quality Control

Our Ethyl (1R,2S)-2-Cyanocyclopropane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with full specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.