Description

5-Hydroxy-4,4-Dimethyl-3-Oxopentanenitrile is a versatile and high-value specialty nitrile compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both hydroxyl and oxo functional groups adjacent to the nitrile, makes it a valuable precursor for the development of complex molecules. This compound is primarily sought after by research institutions and industrial R&D departments within the pharmaceutical, agrochemical, and fine chemical sectors for constructing heterocyclic frameworks and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those containing pyridine, pyrimidine, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile precursor for manufacturing dyes, pigments, and complex organic ligands for catalysis.
• Academic & Industrial Research: Employed in methodological studies and as a model compound for developing new synthetic routes involving cyano and carbonyl chemistry.
• Material Science Precursor: Potential use in the synthesis of specialized polymers and advanced organic materials.

Basic Information

Product Name	5-Hydroxy-4,4-Dimethyl-3-Oxopentanenitrile
CAS No.	489432-33-9
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	4,4-Dimethyl-5-hydroxy-3-oxopentanenitrile; 3-Oxo-4,4-dimethyl-5-hydroxypentanenitrile; 5-Hydroxy-4,4-dimethyl-3-oxovaleronitrile; 4,4-Dimethyl-3-oxo-5-hydroxypentanenitrile; 3-Cyano-4,4-dimethyl-5-hydroxypentan-2-one; 5-Hydroxy-4,4-dimethyl-3-oxopentanenitrile (primary IUPAC)
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-4,4-Dimethyl-3-Oxopentanenitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.