Description

5-Fluoro-2-(Methoxymethoxy)Phenylboronic Acid is a specialized organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. It is primarily needed by pharmaceutical and agrochemical R&D laboratories for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorinated phenylboronic acid moiety is incorporated for enhanced bioactivity and stability.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	5-Fluoro-2-(Methoxymethoxy)Phenylboronic Acid
CAS No.	488713-34-4
Molecular Formula	C9H12BFO4
Molecular Weight	214.00 g/mol
Synonyms	5-Fluoro-2-(methoxymethoxy)benzeneboronic acid; [5-Fluoro-2-(methoxymethoxy)phenyl]boronic acid; 2-(Methoxymethoxy)-5-fluorophenylboronic acid; 5-Fluoro-2-MOM-phenylboronic acid; 5-Fluoro-2-(MOMoxy)phenylboronic acid; Boronic acid, B-[5-fluoro-2-(methoxymethoxy)phenyl]-; 488713-34-4
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Methoxymethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.