Description

(1S,2S)-Boc-2-Aminocyclohexane Carboxylic Acid is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound is critical for the development of novel pharmaceuticals and bioactive molecules, particularly in peptide mimetics and constrained peptidomimetics. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for creating compounds with specific three-dimensional architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in protease inhibitor and antiviral drug development.
• Peptidomimetic Design: Used to introduce constrained cyclohexane scaffolds into peptide backbones, enhancing metabolic stability and receptor selectivity.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged molecules used in target identification and mechanism-of-action studies.
• Agrochemical Research: Employed in the synthesis of novel herbicides and pesticides with chiral centers for improved efficacy and environmental profile.
• Catalyst and Ligand Synthesis: A precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Fundamental material for methodological development in stereoselective synthesis and medicinal chemistry projects.

Basic Information

Item	Details
Product Name	(1S,2S)-Boc-2-Aminocyclohexane Carboxylic Acid
CAS No.	488703-60-2
Molecular Formula	C₁₂H₂₁NO₄
Molecular Weight	243.30 g/mol
Synonyms	(1S,2S)-1-[(tert-Butoxycarbonyl)amino]cyclohexane-2-carboxylic acid; (1S,2S)-2-(Boc-amino)cyclohexanecarboxylic acid; (1S,2S)-Boc-Ach-OH; (1S,2S)-Boc-2-Ac6c-OH; (1S,2S)-N-Boc-2-aminocyclohexanecarboxylic acid; (1S,2S)-tert-Butyl (2-carboxycyclohexyl)carbamate; (1S,2S)-2-((tert-Butoxycarbonyl)amino)cyclohexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our (1S,2S)-Boc-2-Aminocyclohexane Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and standard methods to verify chemical identity and potency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, chiral excess, and impurity profiles to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.