Description

3'-Hydroxybiphenyl-4-Carbonitrile is a high-purity, functionalized biphenyl derivative characterized by its distinct cyano and phenolic hydroxyl groups. This compound serves as a versatile and critical pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the development of advanced materials, agrochemicals, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its biphenyl core for biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials due to its rigid, planar structure and functional handles for further modification.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with enhanced thermal and mechanical properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce functionalized biphenyl units into target molecules.
• Chemical Research & Development: A valuable compound for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	3'-Hydroxybiphenyl-4-Carbonitrile
CAS No.	486455-27-0
Molecular Formula	C₁₃H₉NO
Molecular Weight	195.22 g/mol
Synonyms	[1,1'-Biphenyl]-3-ol-4-carbonitrile; 4-Cyano-3'-hydroxybiphenyl; 3'-Hydroxy-4-cyanobiphenyl; 4'-Hydroxy-3-cyanobiphenyl; 3-Hydroxy-4'-cyanobiphenyl; 3-Phenyl-4-cyanophenol; 4-Cyano-3-phenylphenol
EINECS	Contact for details

Quality Control

Every batch of 3'-Hydroxybiphenyl-4-Carbonitrile is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.