Description

(S)-C4-Tunephos CAS NO 486429-94-1 is a high-value, chiral phosphine ligand essential for asymmetric catalysis, enabling the precise control of stereochemistry in complex synthetic transformations. Its primary value lies in facilitating the production of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs) with high efficiency and selectivity. This compound is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require advanced chiral auxiliaries for process development and scale-up.

Application

• As a chiral ligand in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Catalyst component for the synthesis of enantiomerically enriched pharmaceutical intermediates.
• Use in the development of novel agrochemicals requiring specific stereochemistry.
• Key reagent in academic and industrial research for methodological development in organic synthesis.
• Facilitator for the production of chiral fine chemicals and specialty materials.
• Component in catalyst systems for asymmetric synthesis on pilot and commercial scales.

Basic Information

Product Name	(S)-C4-Tunephos
CAS No.	486429-94-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(S)-2,2'-Bis(di-tert-butylphosphino)-6,6'-dimethoxy-1,1'-biphenyl; (S)-DTBM-MeOBIPHEP; (S)-C4-Tunephos Ligand; (S)-Di-tert-butyl(6,6'-dimethoxybiphenyl-2,2'-diyl)bisphosphine; (S)-Xyl-P-Phos (related class); Tunephos derivative; Chiral diphosphine ligand C4; (S)-BIPHEP-type ligand
EINECS	Contact for details

Quality Control

Our (S)-C4-Tunephos is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification by HPLC and structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and chiral excess are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This material is easily oxidized; minimize exposure to air during handling and use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.