Description

3-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrazole-carboxylic acid core substituted with fluorinated and methoxylated aromatic rings. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a structural motif in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated pyrazole moiety.
• Chemical Biology & Proteomics: Used as a specialized scaffold or linker in the design of chemical probes for studying enzyme function and protein-protein interactions.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	3-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazole-5-Carboxylic Acid
CAS No.	485798-67-2
Molecular Formula	C11H9FN2O3
Molecular Weight	236.20 g/mol
Synonyms	1H-Pyrazole-5-carboxylic acid, 3-(3-fluoro-4-methoxyphenyl)-; 3-(3-Fluoro-4-methoxyphenyl)-1H-pyrazole-5-carboxylic acid; 5-Carboxy-3-(3-fluoro-4-methoxyphenyl)pyrazole; 3-(3-Fluoro-4-methoxyphenyl)pyrazole-5-carboxylic acid; 485798-67-2; 3-(3-Fluoro-4-methoxyphenyl)-1H-pyrazole-5-carboxylic acid CAS 485798-67-2
EINECS	Contact for details

Quality Control

Our production of 3-(3-Fluoro-4-Methoxyphenyl)-1H-Pyrazole-5-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality system is designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and documentation meet industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.