Description

Bdp Tmr Nhs Ester CAS NO 485397-12-4 is a high-purity, functionalized fluorescent dye derivative designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers requiring precise, stable covalent attachment of the BODIPY TMR fluorophore to biomolecules like proteins, peptides, and oligonucleotides. It is primarily utilized in the life sciences, diagnostics, and pharmaceutical research sectors for developing sensitive assays, imaging probes, and diagnostic kits.

Application

• Bioconjugation & Probe Development: Covalent labeling of antibodies, proteins, and peptides for fluorescence-based immunoassays (e.g., ELISA, Western Blot) and cellular imaging.
• Nucleic Acid Labeling: Synthesis of fluorescently tagged primers, probes, and nucleotides for FISH, PCR, and sequencing applications.
• Diagnostic Kit Manufacturing: Production of key components for in-vitro diagnostic (IVD) devices and lateral flow assays.
• Drug Discovery & High-Throughput Screening (HTS): Creation of fluorescent tracers and molecular probes for target engagement and binding studies.
• Flow Cytometry & Microscopy: Preparation of specific cell surface markers and intracellular staining reagents.
• Material Science: Functionalization of nanoparticles and polymers for the development of advanced sensing materials.

Basic Information

Product Name	Bdp Tmr Nhs Ester
CAS No.	485397-12-4
Molecular Formula	C25H28BF2N3O5
Molecular Weight	511.32 g/mol
Synonyms	BODIPY® TMR NHS Ester; BODIPY 581/591 NHS Ester; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Propionic Acid, Succinimidyl Ester; BDP TMR SE; BODIPY TMR-X, SE; BODIPY® TR NHS Ester; 3-Propionic acid, 4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-, N-succinimidyl ester
EINECS	Contact for details

Quality Control

Every batch of Bdp Tmr Nhs Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and performance consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with standards relevant for research and in-vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Red to dark red solid or powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption (λmax)	~ 544 nm
Emission (λmax)	~ 572 nm
Extinction Coefficient (ε)	~ 74,000 cm⁻¹M⁻¹
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.