Description

4-Acetyl-3-Fluorophenylboronic Acid is a specialized organoboron compound featuring both a boronic acid and an acetyl functional group on a fluorinated aromatic ring. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in cross-coupling reactions. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block for constructing complex fluorinated and acetyl-substituted biphenyl and heterobiaryl structures in organic chemistry.
• Diagnostic Reagent Development: Potential use in synthesizing probes and sensors for biochemical assays due to the boronic acid group's affinity for diols.

Basic Information

Product Name	4-Acetyl-3-Fluorophenylboronic Acid
CAS No.	481725-35-3
Molecular Formula	C8H8BFO3
Molecular Weight	181.96 g/mol
Synonyms	(4-Acetyl-3-fluorophenyl)boronic acid; 3-Fluoro-4-acetylbenzeneboronic acid; 4-Acetyl-3-fluorobenzeneboronic acid; 3-Fluoro-4-acetylphenylboronic acid; Boronic acid, B-(4-acetyl-3-fluorophenyl)-; 481725-35-3; 4-Acetyl-3-fluoro-benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Acetyl-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.