Description

4-Fluoro-3-(Hydroxymethyl)Benzeneboronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both a boronic acid group and a hydroxymethyl substituent on a fluorinated benzene ring, makes it an essential precursor for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in creating biaryl structures common in kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Fluoro-3-(Hydroxymethyl)Benzeneboronic Acid
CAS No.	481681-02-1
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(4-Fluoro-3-(hydroxymethyl)phenyl)boronic acid; 3-(Hydroxymethyl)-4-fluorobenzeneboronic acid; 4-Fluoro-3-(hydroxymethyl)phenylboronic acid; 4-Fluoro-3-hydroxymethylbenzeneboronic Acid; B-(4-Fluoro-3-(hydroxymethyl)phenyl)boronic acid; 481681-02-1; 4-Fluoro-3-hydroxyMethylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Hydroxymethyl)Benzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.