Description

2-Bromo-4-(Trifluoromethyl)Benzyl Chloride is a versatile and highly reactive halogenated benzyl building block. This compound is valued for its ability to introduce both bromine and chloromethyl functional groups into target molecules, enabling the synthesis of complex intermediates. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules containing trifluoromethyl and halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the benzyl chloride moiety facilitates further derivatization.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of novel monomers and polymers with specific electronic or hydrophobic properties imparted by the trifluoromethyl group.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research settings due to its reactive benzyl chloride handle.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Benzyl Chloride
CAS No.	480438-96-8
Molecular Formula	C8H5BrClF3
Molecular Weight	273.48 g/mol
Synonyms	1-(Bromomethyl)-2-bromo-4-(trifluoromethyl)benzene; α-Bromo-2-bromo-α,α,α-trifluoro-p-xylene; 2-Bromo-α-(chloromethyl)-4-(trifluoromethyl)benzene; (2-Bromo-4-(trifluoromethyl)phenyl)methyl chloride; Benzene, 1-(bromomethyl)-2-bromo-4-(trifluoromethyl)-; 2-Bromo-4-trifluoromethylbenzyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Benzyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.