Description

1,3,4,6-Tetra-O-acetyl-2-O-nonafluorobutanesulfonyl-β-D-mannopyranose is a highly specialized, fluorinated carbohydrate derivative used as a critical synthetic intermediate. This compound is valued for its role in introducing the nonafluorobutanesulfonyl (nonaflate) protecting group, which is exceptionally effective for selective functionalization in complex organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for glycosylation reactions and prodrug development.
• Agrochemical Research: Employed in the creation of advanced, fluorinated pesticide and herbicide candidates to enhance biological activity and environmental stability.
• Glycochemistry & Glycobiology: Used as a versatile mannose donor for the controlled synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Fluorine Chemistry: Acts as a precursor for introducing fluorine-rich motifs into target molecules, leveraging the unique properties of the nonaflate leaving group.
• Material Science: Applied in the development of specialty polymers and surface-modifying agents where fluorinated sugar units impart specific characteristics.
• Process Chemistry & Scale-up: Suitable for optimization and scaling of synthetic routes requiring robust and selective protecting group strategies.

Basic Information

Item	Details
Product Name	1,3,4,6-Tetra-O-acetyl-2-O-nonafluorobutanesulfonyl-β-D-mannopyranose
CAS No.	480438-48-0
Molecular Formula	C₁₈H₁₇F₉O₁₃S
Molecular Weight	692.37 g/mol
Synonyms	2-O-Nonafluorobutanesulfonyl-1,3,4,6-tetra-O-acetyl-β-D-mannopyranose; 1,3,4,6-Tetra-O-acetyl-2-O-(nonafluorobutanesulfonyl)-β-D-mannose; D-Mannose, 2-O-[(1,1,2,2,3,3,4,4,4-nonafluorobutyl)sulfonyl]-, 1,3,4,6-tetraacetate; Mannose nonaflate tetraacetate; β-D-Mannopyranose, 2-O-[(nonafluorobutyl)sulfonyl]-, 1,3,4,6-tetraacetate; 2-O-(Nonafluorobutanesulfonyl)tetraacetylmannose; Tetraacetylmannose nonaflate
EINECS	Contact for details

Quality Control

Our 1,3,4,6-Tetra-O-acetyl-2-O-nonafluorobutanesulfonyl-β-D-mannopyranose is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including NMR and HPLC. We are committed to meeting the exacting standards required for synthetic chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require desiccant. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.