Description

(S)-3-o-Benzyl-5-Hydroxy-1-Cyanopentane is a high-purity chiral intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing specific stereocenters in target compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in neurological and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce the desired (S)-configuration into target molecules.
• Peptidomimetic Research: Serves as a constrained scaffold or backbone component in the design and synthesis of peptide mimics for drug discovery.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for activity.
• Ligand and Catalyst Development: Utilized as a precursor for synthesizing novel chiral ligands and organocatalysts.
• Academic & Contract Research: Essential for medicinal chemistry programs and process chemistry optimization in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	(S)-3-o-Benzyl-5-Hydroxy-1-Cyanopentane
CAS No.	480424-90-6
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	(S)-5-Hydroxy-3-(phenylmethoxy)pentanenitrile; (S)-3-(Benzyloxy)-5-hydroxyvaleronitrile; (S)-5-Hydroxy-3-(benzyloxy)pentanenitrile; (3S)-3-(Benzyloxy)-5-hydroxypentanenitrile; (S)-3-Benzyloxy-5-hydroxypentanenitrile; Benzyl (S)-5-cyano-3-hydroxypentyl ether; (S)-3-O-Benzyl-5-hydroxy-1-cyanopentane
EINECS	Contact for details

Quality Control

Our (S)-3-o-Benzyl-5-Hydroxy-1-Cyanopentane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.