Description

3-Bromo-5-(Trifluoromethyl)Benzeneboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for modern cross-coupling reactions, enabling the efficient construction of complex molecules for advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials chemists in the synthesis of novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to create biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl and halogenated aromatic motifs.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic frameworks.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
• Chemical Biology & Medicinal Chemistry: Facilitates the creation of molecular probes and tool compounds for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, functionalized aromatic boronic esters.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethyl)Benzeneboronic Acid Pinacol Ester
CAS No.	479411-92-2
Molecular Formula	C13H15BBrF3O2
Molecular Weight	350.97 g/mol
Synonyms	3-Bromo-5-(trifluoromethyl)phenylboronic acid pinacol ester; (3-Bromo-5-(trifluoromethyl)phenyl)boronic acid pinacol ester; 3-Bromo-5-trifluoromethylbenzeneboronic acid pinacol ester; 3-Bromo-α,α,α-trifluoro-m-tolylboronic acid pinacol ester; 2-(3-Bromo-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(3-Bromo-5-(trifluoromethyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.