Description

2-Pyrrolidineacetonitrile,1-Methyl-5-Oxo-,(2S)-(9Ci) is a high-purity, chiral nitrile derivative of proline, serving as a sophisticated building block in advanced organic synthesis. Its value lies in its stereochemical integrity and functional group compatibility, enabling the construction of complex molecular architectures with high precision. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, enzyme modulators, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides.
• Asymmetric Catalysis: Employed as a precursor or ligand in the design of chiral catalysts for stereoselective transformations.
• Peptidomimetics: Serves as a constrained proline analog for constructing peptide-like structures with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological mechanisms.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-Pyrrolidineacetonitrile,1-Methyl-5-Oxo-,(2S)-(9Ci)
CAS No.	479411-60-4
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	(2S)-1-Methyl-5-oxopyrrolidine-2-acetonitrile; (S)-1-Methyl-5-oxopyrrolidine-2-acetonitrile; 1-Methyl-5-oxo-(S)-2-pyrrolidineacetonitrile; L-Proline, 5-oxo-, nitrile, N-methyl-; (S)-1-Methyl-2-(cyanomethyl)-5-pyrrolidinone; 2-Pyrrolidineacetonitrile, 1-methyl-5-oxo-, (S)-; Prolinamide, N-methyl-5-oxo-, nitrile, (S)-
EINECS	Contact for details

Quality Control

Every batch of 2-Pyrrolidineacetonitrile,1-Methyl-5-Oxo-,(2S)-(9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, NMR, and GC/MS, to ensure identity, purity, and enantiomeric excess meet the stringent requirements of research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.