Description

Rec β-Defensin 2 (Human) is a recombinant form of the human antimicrobial peptide, β-Defensin 2. This high-purity, biologically active peptide plays a critical role in innate immune defense, offering significant value for research and therapeutic development. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors focusing on immunology, antimicrobial agents, and novel therapeutic formulations.

Application

• Immunological Research: Used as a key reagent in studies of innate immunity, host defense mechanisms, and inflammatory responses.
• Antimicrobial Studies: Investigated for its broad-spectrum activity against bacteria, fungi, and viruses in vitro.
• Drug Discovery & Development: Serves as a lead compound or model for developing new anti-infective and immunomodulatory therapeutics.
• Biomaterial & Wound Healing: Incorporated into coatings and formulations designed to prevent infection and promote healing in medical devices and dressings.
• Cell Culture & Assay Development: Utilized in cell-based assays to study peptide function and signal transduction pathways.
• Diagnostic Development: Potential use as a biomarker or component in diagnostic kits for certain infectious or inflammatory conditions.

Basic Information

Product Name	Rec β-Defensin 2 (Human)
CAS No.	479328-13-7
Molecular Formula	C205H328N62O64S6
Molecular Weight	~ 4.3 kDa
Synonyms	Human β-Defensin 2; HBD-2; DEFB4A; DEFB102; BD-2; Skin-Antimicrobial Peptide 1; SAP1; Recombinant Human β-Defensin 2; Antimicrobial Peptide HBD-2; C20orf57
EINECS	Contact for details

Quality Control

Our Rec β-Defensin 2 (Human) is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is subjected to comprehensive analytical testing, including HPLC for purity assessment, mass spectrometry for identity confirmation, and endotoxin level analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee product integrity for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Biological Activity	Determined by antimicrobial assay
Endotoxin Level	< 1.0 EU/μg
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.