Description

Hydroxythiohomosildenafil is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest for its structural relationship to PDE5 inhibitors, making it a valuable building block in advanced pharmaceutical synthesis and pharmacological research. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of active pharmaceutical ingredients (APIs) targeting specific enzyme pathways.
• Biochemical Research: Used as a reference standard or experimental compound in pharmacological studies to investigate enzyme inhibition and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating novel molecular entities with potential therapeutic applications.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories using techniques like HPLC and LC-MS.
• Academic Research: Supports chemical and biological research in university and institutional settings focused on medicinal chemistry and drug discovery.

Basic Information

Product Name	Hydroxythiohomosildenafil
CAS No.	479073-82-0
Molecular Formula	C23H32N6O4S
Molecular Weight	488.60 g/mol
Synonyms	Hydroxythiohomosildenafil; 2-[2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one; Thiohydroxyhomosildenafil; A homologue of sildenafil analogue; Research compound 479073-82-0
EINECS	Contact for details

Quality Control

Our Hydroxythiohomosildenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.