Description

6-Deoxy-L-[2-13C]Mannose Monohydrate is a stable isotope-labeled derivative of the monosaccharide 6-deoxy-L-mannose, specifically enriched with carbon-13 at the C-2 position. This high-purity labeled compound is essential for advanced metabolic and biochemical research, providing a critical tracer for precise pathway analysis. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in isotope dilution mass spectrometry (IDMS), nuclear magnetic resonance (NMR) spectroscopy, and metabolic flux studies.

Application

• Metabolic Pathway Tracing: Used as a carbon-13 labeled tracer in studies of sugar metabolism, glycobiology, and biosynthesis pathways in microbial, plant, and mammalian systems.
• Quantitative Mass Spectrometry: Serves as a critical internal standard for Isotope Dilution Mass Spectrometry (IDMS) to ensure accurate quantification of 6-deoxy sugars and related metabolites in complex biological matrices.
• NMR Spectroscopy: Provides a non-radioactive, stable isotope probe for structural elucidation and dynamic studies of carbohydrate-containing molecules via 13C-NMR.
• Pharmaceutical R&D: Employed in the research and development of novel therapeutics, including antibiotics and antiviral agents that target sugar metabolism or glycoconjugate synthesis.
• Biochemical Research: Facilitates the study of enzyme mechanisms (e.g., dehydratases, epimerases) involved in the biosynthesis of deoxy and dideoxy sugars.
• Diagnostic Agent Development: Potential use in the formulation of advanced diagnostic probes and imaging agents for medical research.

Basic Information

Product Name	6-Deoxy-L-[2-13C]Mannose Monohydrate
CAS No.	478511-51-2
Molecular Formula	C513CH12O5 • H2O
Molecular Weight	182.15 g/mol (for 13C1 isotopologue)
Synonyms	L-[2-13C]-6-Deoxymannose Monohydrate; 6-Deoxy-L-mannose-2-13C monohydrate; (2R,3S,4S,5S)-2,3,4,5-Tetrahydroxyhexanal-2-13C Monohydrate; L-Rhamnose-2-13C (6-deoxy-L-mannose-2-13C); 6-Deoxy-L-[2-13C]mannopyranose Monohydrate; Isotopically Labeled L-Rhamnose; [2-13C]-6-Deoxy-L-mannose Hydrate
EINECS	Contact for details

Quality Control

Every batch of our 6-Deoxy-L-[2-13C]Mannose Monohydrate is manufactured and analyzed under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing, including NMR and MS for isotopic enrichment verification and HPLC for chemical purity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic purity, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C at C-2
Water Content (KF)	Theoretical (Monohydrate) or as per COA
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.