Description

Kisspeptin 10 (Rat) CAS NO 478507-53-8 is a bioactive decapeptide fragment of the kisspeptin protein, a key regulator of the hypothalamic-pituitary-gonadal axis. This high-purity peptide is essential for advanced research in neuroendocrinology and reproductive biology, enabling precise study of gonadotropin-releasing hormone (GnRH) secretion mechanisms. It is a critical reagent for pharmaceutical R&D, academic institutions, and biotechnology companies focused on developing novel therapeutics for fertility disorders and hormone-dependent conditions.

Application

• Neuroendocrine Research: Fundamental studies on the regulation of GnRH neuron activity and pulsatile hormone release.
• Reproductive Biology Studies: Investigation of puberty onset, ovulation cycles, and spermatogenesis in preclinical models.
• Drug Discovery & Development: Target validation and screening for novel therapeutics addressing infertility, polycystic ovary syndrome (PCOS), and hormone-related cancers.
• In Vitro Assay Development: Used as a standard or stimulant in cell-based assays (e.g., luciferase reporter assays) to study kisspeptin receptor (KISS1R) signaling pathways.
• Veterinary Research: Applied in studies of reproductive management and breeding cycles in animals.
• Metabolic Research: Exploring the interplay between energy balance, metabolism, and reproductive function.

Basic Information

Product Name	Kisspeptin 10 (Rat)
CAS No.	478507-53-8
Molecular Formula	C₆₀H₈₆N₁₈O₁₄
Molecular Weight	1267.5 g/mol
Synonyms	Kisspeptin-10 (rat); Metastin (45-54) (rat); Kp-10 (rat); Kiss-1 (112-121) (rat); Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ (rat); Kisspeptin 10 rat; KISS1 (112-121) amide (rat); Contact for details on additional aliases.
EINECS	Contact for details

Quality Control

Our Kisspeptin 10 (Rat) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. We provide full traceability and ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.