Description

4,5-Dimethoxy-2-(5-Oxo-2-Thioxo-1-Imidazolidinyl)Benzenecarbonitrile is a high-value, heterocyclic organic compound featuring a unique benzonitrile core fused with a thiohydantoin moiety. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in synthetic organic chemistry. It is primarily sought after by research institutions and chemical manufacturers engaged in the development of novel therapeutic agents and fine chemicals. The compound's structure is pivotal for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, or possessing kinase inhibitory activity.
• Agrochemical Research: Used as a building block for developing new active ingredients in herbicides, fungicides, or plant growth regulators, leveraging its heterocyclic scaffold.
• Organic Synthesis & Material Science: Acts as a versatile synthon for constructing complex heterocycles, dyes, or functional materials due to its reactive nitrile and thioamide groups.
• Biochemical Tool Compound: Employed in life science research as a probe or inhibitor to study specific enzymatic pathways or biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this precise chemical entity.

Basic Information

Item	Detail
Product Name	4,5-Dimethoxy-2-(5-Oxo-2-Thioxo-1-Imidazolidinyl)Benzenecarbonitrile
CAS No.	478039-80-4
Molecular Formula	C₁₂H₁₁N₃O₃S
Molecular Weight	277.30 g/mol
Synonyms	2-(4,5-Dimethoxy-2-cyanophenyl)-2-thioxoimidazolidin-4-one; 2-(4,5-Dimethoxy-2-cyanophenyl)-2-thiohydantoin; 4,5-Dimethoxy-2-(2-thioxo-4-oxo-1-imidazolidinyl)benzonitrile; 4,5-Dimethoxy-2-(5-oxo-2-thioxoimidazolidin-1-yl)benzonitrile; 1-(4,5-Dimethoxy-2-cyanophenyl)-2-thiohydantoin; Benzonitrile, 4,5-dimethoxy-2-(5-oxo-2-thioxo-1-imidazolidinyl)-; Thiohydantoin derivative (CAS 478039-80-4)
EINECS	Contact for details

Quality Control

Our production of 4,5-Dimethoxy-2-(5-Oxo-2-Thioxo-1-Imidazolidinyl)Benzenecarbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or manufacturing specifications. Our quality system is designed to support cGMP (current Good Manufacturing Practice) standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.